Chang-Ning Hao, Jing-Juan Huang, Yi-Qin Shi, Xian-Wu Cheng, Rui-Lin Li, Wei Lu, Yi-Zhun Zhu, Jun-Li Duan

Abstract: 

Extracorporeal pulsed electromagnetic field (PEMF) has been shown the ability to improve regenerationn in various ischemic episodes. Here, we examined whether PEMF therapy facilitate cardiac recovery in rat myocardial infarction (MI), and the cellular/molecular mechanisms underlying PEMF-related therapy was further investigated. 

The MI rats were exposed to active PEMF for 4 cycles per day (8 minutes/cycle, 30 ± 3 Hz, 5 mT) after MI induction. The data demonstrated that PEMF treatment significantly inhibited cardiac apoptosis and improved cardiac systolic function. Moreover, PEMF treatment increased capillary density, the levels of vascular endothelial growth factor (VEGF) and hypoxic inducible factor-1α in infarct border zone. Furthermore, the number and function of circulating endothelial progenitor cells were advanced in PEMF treating rats.

In vitro, PEMF induced the degree of human umbilical venous endothelial cells tubulization and increased soluble pro-angiogenic factor secretion (VEGF and nitric oxide). In conclusion, PEMF therapy preserves cardiac systolic function, inhibits apoptosis and trigger postnatal neovascularization in ischemic myocardium.

Keywords: Pulsed electromagnetic field, cardiac function, angiogenesis, apoptosis, ischemic myocardium

Marko S. Markov
Research International, Williamsville, New York, USA


Various types of magnetic and electromagnetic fields are now in successful use in modern medicine. Electromagnetic therapy carries the promise to heal numerous health problems, even where conventional medicine has failed. Today, magnetotherapy provides a non invasive, safe, and easy method to directly treat the site of injury, the source of pain and inflammation, and a variety of diseases and pathologies. Millions of people worldwide have received help in treatment of the musculoskeletal system, as well as for pain relief. Pulsed electromagnetic fields are one important modality in magnetotherapy. Recent technological innovations, implementing advancements in computer technologies, offer excellent state-of-the-art therapy.


Keywords Pulsed electromagnetic fields; Therapy.

Summary. Therapy with electromagnetic fields has a very old tradition in medicine. The indications are widespread, whereas little is known about the effects. Controlled randomizied studies with positive results for pulsed electromagnetic fields (PEMF) are available for osteotomies, the healing of skin wounds, and osteoarthritis. Comparison of the studies is difficult because of the different doses applied and intervals of therapy. Therefore recommendations regarding an optimal dosis and interval are, depending on the disease, quite variable.

.
Key words: PEMF, indications, randomized studies.

M. Fini, G. Giavaresi, A. Carpi, A. Nicolini, S. Setti, R. Giardino

 

Abstract

Osteoarthritis (OA) is the most common disorder of the musculoskeletal system and is a consequence of mechanical and biological events that destabilize tissue homeostasis in articular joints. Controlling chondrocyte death and apoptosis, function, response to anabolic and catabolic stimuli, matrix synthesis or degradation and inflammation is the most important target of potential chondroprotective treatment, aimed to retard or stabilize the progression of OA. Although many drugs or substances have been recently introduced for the treatment of OA, the majority of them relieve pain and increase function, but do not modify the complex pathological processes that occur in these tissues. Pulsed electromagnetic fields (PEMFs) have a number of well-documented physiological effects on cells and tissues including the upregulation of gene expression of members of the transforming growth factor b super family, the increase in glycosaminoglycan levels, and an antiinflammatory action. Therefore, there is a strong rationale supporting the in vivo use of biophysical stimulation with PEMFs for the treatment of OA. In the present paper some recent experimental in vitro and in vivo data on the effect of PEMFs on articular cartilage were reviewed.

These data strongly support the clinical use of PEMFs in OA patients.

Therapeutic Uses of Electromagnetic Fields
A. Bone Repair
B. Wound Repair
C. Pain Management
D. Depression, Anxiety Disorders, Insomnia
E. Protection from Anoxia (Protection for the Heart)

Arthur A. Pilla

It is now commonplace to learn of the successful use of weak non-thermal electromagnetic fields (EMF) in the quest to heal, or relieve the symptoms of, a variety of debilitating ailments. This review will attempt to give the reader an introduction and assessment of EMF modalities which have demonstrated therapeutic benefit for bone and wound repair and chronic and acute pain relief.

Jolanta Kaszuba-Zwoińska, Edyta Zdziłowska, Paulina Chorobik, Zofia Słodowska-Hajduk, Kajetan Juszczak, Wiesław Zaraska, Piotr J. Thor

Abstract

Background. A pulsing electromagnetic field (PEMF) influenced the viability of proliferating in vitro peripheral blood mononuclear cells isolated from Crohn’s disease patients by induction of cell death but did not cause any vital changes in the cells from healthy donors. Experiments with lymphoid cell line U937 have shown a protective effect of PEMF on puromycin-treated cells.

 

Objectives. The current study aimed to investigate the influence of PEMF on native proliferating leukocytes originating from newly-diagnosed acute myelogenous leukemia (AML) patients.

 

Results. Results indicated an increase of Annexin V-positive as well as double stained- and 7-AAD-positive cells after exposure to threefold PEMF stimulation.

 

Conclusions. A low-frequency pulsing electromagnetic field induces cell death in native proliferating cells isolated from AML patients. The increased vulnerability of proliferating PBMCs may be potentially applied in the therapy of AML

 

Key words: pulsing electromagnetic field, acute myelogenous leukemia, apoptosis, necrosis.

Abstract
Electromagnetic therapy is a non-invasive and safe approach for the management of several pathological conditions including neurodegenerative diseases. Parkinson’s disease is a neurodegenerative pathology caused by abnormal degeneration of dopaminergic neurons in the ventral tegmental area and substantia nigra pars compacta in the midbrain resulting in damage to the basal ganglia. Electromagnetic therapy has been extensively used in the clinical setting in the form of transcranial magnetic stimulation, repetitive transcranial magnetic stimulation, high-frequency transcranial magnetic stimulation and pulsed electromagnetic field therapy which can also be used in the domestic setting. In this review, we discuss the mechanisms and therapeutic applications of electromagnetic therapy to alleviate motor and non-motor deficits that characterize Parkinson’s disease.


Keywords: Parkinson’s disease, Electromagnetic therapy, Transcranial magnetic stimulation, Repetitive transcranial magnetic stimulation, High-frequency transcranial magnetic stimulation, Pulsed electromagnetic field therapy

  • Pineal-hypothalamic tract mediation of picotesla magnetic fields in the treatment of neurological disorders.

  • Yawning and stretching induced by transcranial application of AC pulsed electromagnetic fields in Parkinson's disease.

  • AC pulsed electromagnetic fields-induced sexual arousal and penile erections in Parkinson's disease.

  • Treatment with AC pulsed electromagnetic fields improves olfactory function in Parkinson's disease.

  • Reversal of the bicycle drawing direction in Parkinson's disease by AC pulsed electromagnetic fields.

  • Transcranial AC pulsed applications of weak electromagnetic fields reduces freezing and falling in progressive supranuclear palsy: a case report.

  • Reversal of a body image disorder (macrosomatognosia) in Parkinson's disease by treatment with AC pulsed electromagnetic fields.

  • Speech impairment in Parkinson's disease is improved by transcranial application of electromagnetic fields.

  • Treatment with AC pulsed electromagnetic fields improves the response to levodopa in Parkinson's disease.

  • Reversal of cognitive impairment in an elderly parkinsonian patient by transcranial application of picotesla electromagnetic fields.

By Dr. William Pawluk M.D.


As I talk to people who purchase magnetic field systems I frequently get asked "when will I likely see a result?"

The other question is "why is the device not helping?"
Both of these questions are actually related. The answers require an understanding of how pulsed magnetic fields work when applied for specific health circumstances, and considering the individual body.

William Pawluk, MD, MSc

 

Summary

PEMF’s of various kinds and strengths have been found to have good results in a wide array of painful conditions. There is little risk when compared to the potential invasiveness of other therapies and the risk of toxicity, addiction and complications from medications.

Clearly more research is needed to elaborate mechanisms and optimal treatment parameters. Many studies that have been reported here have been controlled trials and many have been double blind placebo. Medical practitioners are becoming gradually aware of the potential of MF’s to successfully treat or significantly benefit the myriad of problems presented to them.

Effect of Pulsed Electromagnetic Field (PEMF) on Infarct Size and Inflammation After Cerebral Ischemia in Mice

Juan Carlos Pena-Philippides & Yirong Yang & Olga Bragina & Sean Hagberg & Edwin Nemoto & Tamara Roitbak

 

Abstract Pulsed electromagnetic fields (PEMF) have been demonstrated to have anti-inflammatory and pro-regenerative effects in animals and humans. We used the FDA-approved Sofpulse™ (Ivivi Health Sciences, LLC) to study effect of PEMF on infarct size and poststroke inflammation following distal middle cerebral artery occlusion (dMCAO) in mice. Electromagnetic field was applied within 30–45 min after ischemic brain damage and utilized twice a day for 21 consecutive days. Ischemic infarct size was assessed using MRI and histological analysis. At 21 days after dMCAO, the infarct size was significantly (by 26 %) smaller in PEMF-treated animals as compared to controls. Neuroinflammation in these animals was evaluated using specialized cytokine/chemokine PCR array. We demonstrate that PEMF significantly influenced expression profile of pro- and anti-inflammatory factors in the hemisphere ipsilateral to ischemic damage. Importantly, expression of gene encoding major pro-inflammatory cytokine IL-1 was significantly reduced, while expression of major anti-inflammatory IL-10 was significantly increased. PEMF application significantly downregulated genes encoding members of the major pro-apoptotic tumor necrosis factor (TNF) superfamily indicating that the treatment could have both anti-inflammatory and anti-apoptotic effects. Both reduction of infarct size and influence on neuroinflammation could have a potentially important positive impact on the poststroke recovery process, implicating PEMF as a possible adjunctive therapy for stroke patients.

Keywords. Pulsed electromagnetic field .dMCAO . Ischemic infarct . Neuroinflammation

Treatment with PEMF appears to be disease-modifying in this model of osteoarthritis. Since TGFβ is believed to upregulate gene expression for aggrecan, downregulate matrix metalloprotease and IL-1 activity, and upregulate inhibitors of matrix metalloprotease,
the stimulation of TGFβ may be a mechanism through which PEMF favorably affects cartilage homeostasis.

PEMF exposure significantly increased PG synthesis ranging from 12% at 4 h to 17% at 24 h of exposure. At all the magnetic field peak amplitude values, a significant PG synthesis increase was measured in PEMF-exposed explants compared to controls, with maximal effect at 1.5 mT. No effect of pulse frequency was observed on PG synthesis stimulation.
Conclusions: The results of this study show the range of exposure length, PEMF amplitude, pulse frequency which can stimulate cartilage PG synthesis, and suggest optimal exposure parameters which may be useful for cartilage repair in in vivo experiments and clinical application.

Pulsed Electromagnetic Fields for Treating Osteo-arthritis

The basic and clinical research in this field, while somewhat limited, supports the insightful application of pulsed electromagnetic fields to ameliorate pain and disability due to osteo-arthritis.
Further basic and clinical research to validate the use of pulsed electromagnetic fields in facilitating function and possibly in facilitating joint reparative processes in osteo-arthritis, as well the lessening of osteo-arthritic joint
pain and joint dysfunction is indicated.

In summary, we demonstrate that PEMF therapy successfully suppressed the induction of IL-1! in two models of TBI in rats. Therefore, it is possible that this type of therapy will improve outcomes after brain injury in humans. Additional studies examining the effect of PEMF signals on neuronal survival and neurological outcomes after TBI are warranted.

Traumatic Brain Injury (TBI) is a major cause of morbidity and mortality in civilian and military populations.
Interleukin-1beta (IL-1!) is a pro-inflammatory cytokine with a key role in the inflammatory response following TBI and studies indicate that attenuation of this cytokine improves behavioral outcomes.
Pulsed electromagnetic fields (PEMF) can reduce inflammation after soft tissue injuries in animals and humans. Therefore, we explored whether PEMF signals could alter the course of IL-1! production in rats subjected to closed-head contusive weight-drop injuries (Marmarou method) and penetrating needle-stick brain injuries. Protein levels, measured by the Biorad assay, were not altered by injuries or PEMF treatment. In addition, we verified that IL-1! levels in cerebrospinal fluid (CSF) were proportional to injury severity in the contusion model. Results demonstrate that PEMF treatment attenuated IL-1! levels up to 10-fold in CSF within 6 h after contusive injury and also significantly suppressed IL-1! within 17–24 h after penetrating injury. In contrast, no differences in IL-1! were seen between PEMF-treated and control groups in brain homogenates. To the authors’ knowledge, this is the first report of the use of PEMF to modulate an inflammatory cytokine after TBI. These results warrant further studies to assess the effects of PEMF on other inflammatory markers and functional outcomes.

PEMFs of various kinds, high intensity/low intensity and/or high frequency/low frequency show potential for dramatic benefits without toxic or invasive treatments. Generally, the cost of treatments, that are available to be applied in the home setting on a regular basis, would amount to pennies per day. This would decrease the burden not only on the patient with AD but also on their caregivers.
Considering that this is a progressive condition, usually leading to death, for which there is no currently known therapy, involving millions of people, PEMFs certainly appear worth trying. Needless to say, the more advanced the condition is already, the less favorable the results are going to be.

Marko S. Markov

Magnetic and electromagnetic fields are now recognized by the 21st century medicine as real physical entities that promise the healing of various health problems, even when conventional medicine has failed. Today magnetotherapy provides a non-invasive, safe, and easy method to directly treat the site of injury, the source of pain and inflammation, and other types of diseases and pathologies. Millions of people worldwide have received help in treatment of musculoskeletal system, as well as pain relief. Pulsed electromagnetic fields are one important modality in magnetotherapy and recent technological innovations, such as Curatron pulsed electromagnetic field devices, offer excellent, state of the art computer controlled therapy system. In this article the development, state of the art and future of pulsed electromagnetic field therapy are discussed. 

 

One of the very important issues that engineers and biophysicists neglect, is the frequency spectrum of the signal. At any PEMF, a large spectrum of harmonics, up to 3 kHz exists with the first harmonic usually having the amplitude close to 20% of the amplitude of basic signal. In that aspect, the computerized system, offered and already in use, by Curatron is of great importance. The computer technology allows a collection of feedback information, analysis and monitoring of the signal during the entire treatment session and opportunities for Furrier analysis of the signal during the use. Shortly, computer link to PEMF is the future of the therapy with PEMF.

Abstracts

  • Biophysical stimulation in osteonecrosis of the femoral head: Stimulation with pulsed electromagnetic fields (PEMFs) has been shown to be useful for enhancing bone repair and for exerting a chondroprotective effect on articular cartilage. The long term effect of PEMF stimulation may be to promote osteogenic activity at the necrotic area and prevent trabecular fracture and subchondral bone collapse. PEMF stimulation represents an important therapeutic opportunity to resolve the Ficat stage-I or II disease or at least to delay the time until joint replacement becomes necessary.

  • The efficacy of pulsed electromagnetic fields used alone in the treatment of femoral head osteonecrosis: a report of two cases

  • Electromagnetic fields and magnets. Investigational treatment for musculoskeletal disorders

  • Effects of pulsed electromagnetic fields on Steinberg ratings of femoral head osteonecrosis

  • Effects of pulsed electromagnetic fields on human osteoblastlike cells (MG-63): a pilot study

This article highlights recent research on the beneficial use of selected low frequency electromagnetic fields (EMF) as a safe alternative therapy for treatment of cancer and other health problems. It is shown that EMF therapy provides a safe alternative and adjunct modality for the treatment of cancer and other health problems, and therefore, research in this field deserves more support.

PEMF therapy various abstracts

The present study examined the effect of applying a pulsed electromagnetic field (PEMF) on bone formation around a rough-surfaced dental implant. A dental implant was inserted into the femur of Japanese white rabbits bilaterally. A PEMF with a pulse width of 25 ms and a pulse frequency of 100 Hz was applied. PEMF stimulation was applied for 4 h or 8 h per day, at a magnetic intensity of 0.2 mT, 0.3 mT or 0.8 mT. The animals were sacrificed 1, 2 or 4 weeks after implantation. After staining the resin sections with 2% basic fuchsin and 0.1% methylene blue, newly formed bone around the implant on tissue sections was evaluated by computer image analysis. The bone contact ratios of the PEMF-treated femurs were significantly larger than those of the control groups. Both the bone contact ratio and bone area ratio of the 0.2 mT- and 0.3 mT treated femurs were significantly larger than the respective value of the 0.8 mT treated femurs (P°0.001). No significant difference in bone contact ratio or bone area ratio was observed whether PEMF was applied for 4 h/day or 8 h/day. Although a significantly greater amount of bone had formed around the implant of the 2-week treated femurs than the 1-week treated femurs, no significant difference was observed between the 2-week and 4-week treated femurs. These results suggest that PEMF stimulation may be useful for promoting bone formation around rough-surfaced dental implants. It is important to select the proper magnetic intensity, duration per day, and length of treatment.

Although bone healing around titanium implants has already been evaluated, the effect of pulsed electromagnetic fields (PEMF) during the period of bone maturation around titanium dental implants has not yet been investigated. The aim of this study was to evaluate the effects of PEMFs on bone formation following the insertion of titanium-dental implants in the rabbit mandibular model.

significant differences in bone osteoblastic activity and new trabecular bone formation were observed between the control group and the PEMF treated group at week 8 (p<0,001). These results indicate that PEMF had an effect on the bone inductive properties in the area surrounding the implant.

We investigated the effect of stimulation with a pulsed electromagnetic field on the osseointegration of hydroxyapatite in cortical bone in rabbits. Implants were inserted into femoral cortical bone and were stimulated for six hours per day for three weeks. Electromagnetic stimulation improved osseointegration of hydroxyapatite compared with animals which did not receive this treatment in terms of direct contact with the bone, the maturity of the bone and mechanical fixation. The highest values of maximum push-out force and ultimate shear strength were observed in the treated group and differed significantly from those of the control group at three weeks.

Dental implants using titanium have greatly advanced through the improvement of designs and surface treatments. Nonetheless, the anatomical limits and physiological changes of the patient are still regarded as obstacles in increasing the success rate of implants further, even with the enhancement of implant products. So there have been many efforts to overcome these limits. The intrinsic potential for bone regeneration can be stimulated through adjuvant treatments with the continuous improvement of implant properties, and this can play an important role in achieving optimum osseointegration toward peripheral bone tissue and securing ultimate long-term implant stability in standard surgical procedures. For this purpose, various chemical, biological, or biophysical measures were developed such as bone grafts, materials, pharmacological agents, growth factors, and bone formation proteins. The biophysical stimulation of bone union includes non-invasive and safe methods. In the beginning, it was developed as a method to enhance the healing of fractures, but later evolved into Pulsed Electromagnetic Field, Low-Intensity Pulsed Ultrasound, and Low-Level Laser Therapy. Their beneficial effects were confirmed in many studies. This study sought to examine bone implant union and its latest trend as well as the biophysical stimulation method to enhance the union. In particular, this study suggested the enhancement of the function of cells and tissues under a disadvantageous bone metabolism environment through such adjunctive stimulation. This study is expected to serve as a treatment guideline for implant bone union under unfavorable circumstances caused by systemic diseases hampering bone metabolism or the host environment.

PEMF seems to reduce pain better than sham PEMF and may be a helpful modality in the treatment of lateral epicondylitis. Although the treatment time is quite long and necessitate compliance, it can be used in patients avoiding invasive approaches. Corticosteroid and anesthetic agent injections can be used in patients for rapid return to activities.

Exposure to a specific pulsed electromagnetic field (PEMF) has been shown to produce analgesic (antinociceptive) effects in many organisms. In a randomized, double-blind, sham-controlled clinical trial, patients with either chronic generalized pain from fibromyalgia (FM) or chronic localized musculoskeletal or inflammatory pain were exposed to a PEMF (400 μT) through a portable device fitted to their head during twice-daily 40 min treatments over seven days. The effect of this PEMF on pain reduction was recorded using a visual analogue scale. A differential effect of PEMF over sham treatment was noticed in patients with FM, which approached statistical significance (P=0.06) despite low numbers (n=17); this effect was not evident in those without FM (P=0.93; n=15). PEMF may be a novel, safe and effective therapeutic tool for use in at least certain subsets of patients with chronic, nonmalignant pain. Clearly, however, a larger randomized, double-blind clinical trial with just FM patients is warranted.

Osteoporosis is becoming a great social and medical problem due to the elderly population. Various forms of prevention and treatment are needed to deal with this problem. It has been found that PEMF is safe and effective in treating osteoporosis. This review concentrates on the progress of recent studies done so far n pulse electromagnetic therapy in the treatment of osreoporosis.

  • Fundamental and practical aspects of therapeutic uses of pulsed electromagnetic fields (PEMFs).

  • Endothelial cell response to pulsed electromagnetic fields: stimulation of growth rate and angiogenesis in vitro.

  • Bone mass is preserved in a critical-sized osteotomy by low energy pulsed electromagnetic fields as quantitated by in vivo micro-computed tomography.

  • Pulsed electromagnetic field treatments enhance the healing of fibular osteotomies.

  • Additive effects of prostaglandin E2 and pulsed electromagnetic fields on fracture healing.

  • The effects of pulsed electromagnetism on fresh fracture healing: osteochondral repair in the rat femoral groove.

  • Beneficial effects of electromagnetic fields.

Abstracts- Pulsed electromagnetic fields for the treatment of bone fractures and acceleration of bone healing.

The aim was to establish the potential efficacy, tolerability and side-effect profile of electromagnetic therapy as an adjunct to conventional dressings in the treatment of venous leg ulcers. Electromagnetic therapy provided significant gains in the healing of venous leg ulcers and reduction in pain.

In depth Studies have been performed into Multiple Sclerosis, providing indications which support the therapeutic use of Pulsing Electromagnetic Field Therapy across many elements of the disease.

The present study, led by associate professor Dr. W. Passath and Prof. Dr. G. Leb of the Medical Clinic of Karl Franzen University, Graz, covered the selection of patients, their treatment as well as all monitoring examinations. In this study it could be shown that the bone density increase initiated by the newly introduced magnetic field therapy achieved for patients with marked osteoporosis improvements of +7.5%, or of +5.8% for all patients, as measured one year after the end of therapy, a result which is most significant as compared with the control group.

These results suggest that PEMFs may be effective treatment for patients after traumatic or ischemic brain injury.

PEMF therapy has been used successfully in the management of postsurgical pain and edema, the

treatment of chronic wounds, and in facilitating vasodilatation and angiogenesis. Using scientific support, the authors present the currently accepted mechanism of action of PEMF therapy.

Conclusions: This review shows that plastic surgeons have at hand a powerful tool with no known side effects for the adjunctive, noninvasive, nonpharmacologic management of postoperative pain and edema. Given the recent rapid advances in development of portable and economical PEMF devices, what has been of most significance to the plastic surgeon is the laboratory and clinical confirmation of decreased pain and swelling following injury or surgery.

Effects of Pulsed Electromagnetic Fields on Interleukin-1 and Postoperative Pain: A Double-Blind, Placebo-Controlled, Pilot Study in Breast Reduction Patients.

Pulsed electromagnetic field therapy significantly reduced postoperative pain and narcotic use in the immediate postoperative period. The reduction of IL-1 in thewoundexudate supports amechanism thatmayinvolve manipulation of the dynamics of endogenous IL-1 in the wound bed by means of a pulsed electromagnetic field effect on nitric oxide signaling, which could impact the speed and quality of wound repair.

William Pawluk, MD, MSc

Research, on humans and animals, has shown that PEMFs alter stress responses by action directly on the nervous system, glands, cells, tissues and organs.

PEMF field exposure induced a predominantly mitogenic effect in the NP cells. While the application of PEMF remains an attractive possibility for the non-invasive treatment of disc disorders, the effective field strength and high level of field control required should be critically evaluated.

Pulsed electromagnetic field therapy is used as an adjuvant therapy in the management of un-united fractures and in osteoarthritis. This treatment has well documented physiological effects on cells and tissues.

PEMF stimulation of osteochondral defects with calcium phosphate scaffold is effective in hyaline cartilage formation. PEMF is a non-invasive and cost effective adjuvant treatment with salvage procedures such as abrasion chondroplasty and subchondral drilling.

Results of bio-mechanical and histologic investigations prove that electromagnetic fields not only prevent bone loss, but also restore bone mass, once lost. The key to rational use of electro-magnetic fields lies in the ability to define the specific treatment parameters (amplitude, frequency, orientation and timing).
Various studies have clearly shown that bone density does increase in osteoporosis-prone patients exposed to specific pulsed electromagnetic fields. Properly applied pulsed electromagnetic fields, if scaled for whole body use, have clear clinical benefits for treatment of osteoporosis.

Effectiveness of pulsed electromagnetic field therapy in lateral epicondylitis

We aimed to investigate the efficacy of pulsed electromagnetic field (PEMF) in lateral epicondylitis comparing the modality with sham PEMF and local steroid injection. PEMF seems to reduce lateral epicondylitis pain better than sham PEMF.

Low-frequency PEMF therapy might improve function, pain, fatigue, and global status in fibromyalgia patients.

specific cognitive symptoms of AD are improved by treatment with EMF of a specific intensity and frequency.

Application of magnetic fields might open new avenues in the management of memory disturbances in the elderly and possibly in AD.

Therapeutic effects of pulsed magnetic fields on joint diseases and osteoarthritis.

The efficacy of pulsed electromagnetic fields in the treatment of femoral head osteonecrosis.

Electromagnetic stimulation as a treatment of tinnitus.

This study demonstrates that pulsed electromagnetic fields are able to accelerate wound healing under diabetic and normal conditions by up-regulation of FGF-2-mediated angiogenesis. They also prevented tissue necrosis in response to a standardized ischemic insult, suggesting that noninvasive angiogenic stimulation by pulsed electromagnetic fields may be useful to prevent ulcer formation, necrosis, and amputation in diabetic patients.

The results suggest a significant beneficial stimulation in the wound healing process in rats treated with PEMF, which could lead to the development of a practical tool for research and clinical use.

Structurally deleterious loss of bone may be slowed or prevented by appropriate use of non-invasive electromagnetic stimulation.

The substantial effects of electrical stimulation in compressing regeneration stagger suggest its use as a clinical tool. Electrical stimulation thus promotes the onset of motor axon regeneration without increasing its speed. This finding suggests a combined approach to improving the outcome of nerve repair, beginning with stimulation to recruit all motoneurons across the repair, followed by other treatments to speed and prolong axonal elongation.

The impact of treatment with magnetic fields on a variety of physical ailments are presented in the following descriptions of recent studies, published in peerreviewed scientific journals.

A wealth of articles on Pulsing Electromagnetic Field therapy (PEMF) technology is available. Following is a selection of abstracts, articles and references on PEMF. This information has been collected to indicate the benefits on the use of pulsing electromagnetic field therapy and many are double blind, placebo controlled studies.

It is concluded that stimulation with an electromagnetic field is a useful adjunctive therapy in the management of skin ulcers.

Dr. W Pawluk

The combination of higher intensity PEMF and occupational therapy improves function, even in patients who had their strokes over a year earlier, and in some cases up to nine years earlier.

Higher intensity PEMF therapy systems that could be considered for stroke management, in the light of the studies above, would include the Curatron XPSE.

The data on this experimental systems in rats indicate that pulsed electromagnetic fields diminish abnormal levels of resorption in disuse osteoporosis and increase rates of bone formation.

Relation to biological activity on nonunion bone ends


Pulsing electromagnetic field therapy is an effective treatment for ununited tibial fractures with good blood supply to the bone ends.

Due to the very high overall success rates by the use of the Curatron PEMF Pulsed Electromagnetic Therapy systems for orthopedic and neurological patients, there are currently evaluations underway also for other uses of these systems e.g. in the field of proctology and wound healing.

This state-of-the-art therapy system has proved to be very important for treatment of many different diseases in a simple way, without the need for any contact with the body of the patients. The therapy applicator is placed above or under the body part of the patient to be treated and the flexibility of the therapy method without any contra indication is extremely easy accepted by the patient. The short overall treatment time guarantees a high patient throughput, which make the Curatron PEMF devices also very attractive for smaller hospitals and private clinics.

Both the pulsed electromagnetic field and therapeutic US were significantly more effective than no treatment. The pulsed electromagnetic field may be applied as an effective and alternative therapy approach in knee osteoarthritis.

Pulsed electromagnetic fields have been applied with success to a wide array of physiologic healing problems. This seems to make a difference in neuroregeneration, in healing of skin wounds, and in the healing of ligaments. It has been demonstrated to make a difference in human soft tissue healing such as epicondylitis and in rotator cuff tendonitis. Our own studies identified that the effect on bone healing occurs early in the healing phase.

there is a strong rationale supporting the in vivo use of biophysical stimulation with PEMFs for the treatment of osteoarthritis. In the present paper some recent experimental in vitro and in vivo data on the effect of PEMFs on articular cartilage were reviewed. These data strongly support the clinical use of PEMFs in OA patients.

The basic and clinical research in this field, while somewhat limited, supports the insightful application of pulsed electromagnetic fields to ameliorate pain and disability due to osteo-arthritis.

It can be implied that pulsed electromagnetic field therapy can become one of the important methods to treat osteoporosis and other related bone diseases. It provides a noninvasive, safe and easy method to directly treat the site of the body concerned and can save many people from undergoing surgery.

Electromagnetic fields do modify biological behavior by inducing electrical changes around and within the cell. The key to rational use of electro-magnetic fields lies in the ability to define the specific treatment parameters (amplitude, frequency, orientation and timing). Various studies have clearly shown that bone density does increase in osteoporosis-prone patients exposed to specific pulsed electromagnetic fields.

Properly applied pulsed electromagnetic fields, if scaled for whole body use, have clear clinical benefits for treatment of osteoporosis.

We aimed to investigate the efficacy of pulsed electromagnetic field (PEMF) in lateral epicondylitis comparing the modality with sham PEMF and local steroid injection.

 

​In conclusion, PEMF seems to reduce pain better than sham PEMF and may be a helpful modality in the treatment of lateral epicondylitis. Although the treatment time is quite long and necessitate compliance, it can be used in patients avoiding invasive approaches. Corticosteroid and anesthetic agent injections can be used in patients for rapid return to activities.

In conclusion, this study has demonstrated a statistically significant benefit in terms of reduction of pain and disability in patients with knee OA resistant to conventional treatment in the absence of significant side-effects.

It was concluded that pulsed electromagnetic fields significantly influence healing in tibial fractures with delayed union.

CONCLUSION: These findings provide some initial support for the use of PEMF exposure in reducing pain in chronic pain populations and warrants continued investigation into the use of PEMF exposure for short-term pain relief.

Despite these limitations, we determined that there was a clear reduction in pain and an improvement in functional status in the PEMF group after therapy. Useful effects recorded in the parameters as a result of the PEMF treatment are promising that PEMF treatment may offer a potential therapeutic adjunct to current COA therapies in the future.

EMF therapy modalities are simple, safe and significantly less costly to the health care system. They offer the ability to treat the underlying pathology rather than simply the symptoms. The time is particularly opportune given the increased incidence of side effects from the use of pharmacological agents. EMF therapeutics will have a profound impact upon health and wellness and their costs worldwide.

Electromagnetic therapy is a non-invasive and safe approach for the management of several pathological conditions including neurodegenerative diseases. Parkinson’s disease is a neurodegenerative pathology caused by abnormal degeneration of dopaminergic neurons in the ventral tegmental area and substantia nigra pars compacta in the midbrain resulting in damage to the basal ganglia. Electromagnetic therapy has been extensively used in the clinical setting in the form of transcranial magnetic stimulation, repetitive transcranial magnetic stimulation, high-frequency transcranial magnetic stimulation and pulsed electromagnetic field therapy which can also be used in the domestic setting. In this review, we discuss the mechanisms and therapeutic applications of electromagnetic therapy to alleviate motor and non-motor deficits that characterize Parkinson’s disease.

Effects of PEMF on muscle recovery via increase of HSP 70 expression after crush injury of rat skeletal muscle

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PEMF Scientific Studies